Check Intently (2)pentobarbital will lessen the extent or effect of suvorexant by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check. Sturdy CYP3A4 inducers may lessen suvorexant efficacy; if elevated suvorexant dose demanded, will not exceed 20 mg/dayCheck Closely (one)pentobarbital will enhance the level or result of clopido